To try to answer you question backspace2062, I don't think it's possible to simulate a floodplain if you don't have any information on it. That being said, it's not absolutely necessary to have a DEM to simulate a floodplain, although that would be the more rigorous approach to follow by using the DEM in MIKE FLOOD (MIKE 21 terrain model + M11 main river bed model) because MIKE 11 is a uni-dimensional model and therefore doesn't accurately model floodplain flow which is typically bi-dimensional. But MIKE 21 is bi-dimensional hence it is able to better model floodplains.
Anyway, in case you are using only MIKE 11 and you have information on a few cross-sections large enough to include the floodplain, you can use those to model it, but you should remember it is an approximation as in reality the flow is likely bi-dimensional.
Best regards,
Ricardo Machado