Hi,
no, I haven't worked on BIOFOR before, but here's how I would tentatively go about it.
The Trickling Filter, MBBR and IFAS models include a biofilm model (and biological process within the biofilm), as well as biological process in liquid phase (only MBBR and IFAS). Beware that the biofilm model is kind of stiff, so you may need to patiently initialise it in order to get an acceptable simulation speed.
None of the standard models describe the hydraulics (upward flow) in great details though: so if this should be essential, you would need to implement this part of the model yourself.